Key publications

  1. Oizel K, Tait-Mulder J, Fernandez-de-Cossio-Diaz J, Pietzke M, Brunton H, Lilla S, Dhayade S, Athineos D, Blanco GR, Sumpton D, Mackay GM, Blyth K, Zanivan SR, Meiser J, Vazquez A. Formate induces a metabolic switch in nucleotide and energy metabolism. Cell Death & Disease 2020; 11(5):310 | PubMed

  2. Kurniawan H, Franchina DG, Guerra L, Bonetti L, Baguet LS, Grusdat M, Schlicker L, Hunewald O, Dostert C, Merz MP, Binsfeld C, Duncan GS, Farinelle S, Nonnenmacher Y, Haigh, J, Das Gupta D, Ewe A, Taskesen R, Halder R, Chen Y, Jaeger C, Ollert M, Wilmes P, Vasiliou V, Harris IS, Knobbe-Thomsen CB, Turner JD, Mak TW, Lohoff M, Meiser J, Hiller K, Brenner D. Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metabolism 2020 | PubMed

  3. Pietzke M, Meiser J, Vazquez A. Formate Metabolism in Health and Disease. Molecular Metabolism 2019; 33:23-37 | PubMed

  4. Meiser J, Kraemer L, Jaeger C, Madry H, Link A, Lepper PM, Hiller K, Schneider JG. Itaconic acid indicates cellular but not systemic immune system activation. Oncotarget 2018; 9(63): 32098-32107 | PubMed

  5. Meiser J, Schuster A, Pietzke M, VandeVoorde J, Athineos D, Oizel K, et al. Increased formate overflow is a hallmark of oxidative cancer. Nature Communication 2018;9(1):1368 | PubMed

  6. Burgos-Barragan G, Wit N*, Meiser J*, Dingler FA, PietzkeM, Mulderrig L, et al. Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. Nature 2017;548(7669):549-54 | PubMed

  7. Meiser J, Tumanov S, Maddocks O, Labuschagne CF, Athineos D, Van Den Broek N, Mackay GM, Gottlieb E, Blyth K, Vousden K et al: Serine one-carbon catabolism with formate overflow. Science Advances 2016, 2(10):e1601273 | PubMed

  8. Meiser J, Kramer L, Sapcariu SC, Battello N, Ghelfi J, D'Herouel AF, Skupin A, Hiller K: Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression. The Journal of Biological Chemistry 2016, 291(8):3932-3946 | PubMed

 

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